Pentobarbital-induced Changes in Drosophila Glutathione S-Transferase D21 mRNA Stability

Drosophila glutathione S-transferase 1-1 shares a region of sequence homology with the maize glutathione S-transferase III.

We have characterized a Drosophila glutathione S-transferase (RX:glutathione R-transferase, EC 2.5.1.18) cDNA encoding a protein of 209 amino acids. The cDNA was expressed in Escherichia coli harboring the expression plasmid construct pGTDml-KK. The active enzyme, designated as Drosophila glutathione S-transferase 1-1, had a specific activity toward 1-chloro-2,4-dinitrobenzene comparable to tha...

Estrogen receptor 1, glutathione S-transferase P1, glutathione S-transferase M1, and glutathione S-transferase T1 genes with dysmenorrhea in Korean female adolescents.

BACKGROUND Dysmenorrhea is the most common gynecologic complaint among adolescent females. We investigated the association between genetic polymorphisms and dysmenorrhea. METHODS A total of 202 postmenarcheal Korean female adolescents 16-17 yr old participated in this study. Genotyping for glutathione S-transferase mu 1 (GSTM1), glutathione S-transferase theta 1 (GSTT1), glutathione S-transfe...

Expression of cytochrome P450 and glutathione S-transferase in human bone marrow mesenchymal stem cells

Currently several studies are being carried out on various properties of mesenchymal stem cells (MSCs)however there are a few investigations about drug metabolizing properties of these cells. The aim of thisstudy was to measure the key factors involved in drug metabolism in human bone marrow MSCs. For thispurpose, cellular glutathione (GSH), glutathione Stransferase (GSTs) and...

Cellular Immune Responses in Sheep against Glutathione S-transferase of Fasciola gigantica

Age - related Changes in Glutathione Concentration , Glutathione Peroxidase , Glutathione - S - Transferase , and Superoxide Dismutase Actiyities in Senescence Accelerated Mice

Age-associated changes in several antioxidative factors were studied in blood and liver from mice prone to accelerated senescence aged O.7 to 1.4 years and mice resistant to acce]erated senescence aged 1.0 to 2.1 years. In both strains, actiyities of hepatic glutathione peroxidase (GSH-Px) and glutathione-Stransferase (GST) decrefised significantly with age, and the actiyity of superoxide dismu...